The Impact of Early Menopause

Posted on:  |  Filed under: Early Menopause, Featured, Female, Menopause


Early menopause can have a significant impact on female health. At the recent World Menopause Congress, Dr Rod Baber, a prominent Australian Ob/Gyn spoke on this topic – the impact of early menopause. Find his summary below:

“Premature Ovarian Insufficiency (POI) is a syndrome of amenorrhea, sex steroid deficiency and elevated gonadotropins in a woman aged more than two standard deviations below the mean age estimated for her reference population. In practical terms it occurs spontaneously in 1% of women before the age of 40. An early menopause (before age 45) will also occur in approximately 5% of women whilst iatrogenic POI will also affect approximately 8% of women prior to age 40 as a result of surgery, radiotherapy or chemotherapy.

Women with early menopause have an increased risk of heart disease, stroke and early death. This risk increase appears to be greater following a surgical menopause. Early menopause also leads to increased risk of osteoporotic fractures , cognitive impairment and Parkinson’s disease , whilst the impact of POI on reproductive and psychological health is substantial. POI is also associated with autoimmune
endocrine disorders including thyroid disease, Addison’s disease and diabetes. Almost 1 in 4 women with POI will develop autoimmune thyroiditis and 3% will develop adrenal insufficiency or diabetes.

There is clear evidence that Hormone Replacement Therapy for early menopause will prevent these adverse health outcomes if it is administered at least until age 45. The 2013 International Menopause Society Global Consensus Statement recommends that HRT be continued in women with Premature Ovarian Insufficiency at least until the age of the natural menopause.”


The booklets below, Natural Progesterone Cream and Testosterone for Women give a general overview on the wide ranging properties of progesterone and testosterone and their use in Hormone Replacement Therapy.

Progesterone for women booklet


Testosterone for women booklet


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