Hormone Solutions

Endometrial Hyperplasia Booklet

Endometrial hyperplasia booklet

Understand your condition

Assess your symptoms

Take the Female progesterone deficiency self assessment

Female Progesterone Deficiency Self Assessment

This test will help with the diagnosis and management of progesterone deficiency in women. It will assess your symptoms and provide you with a series of action steps to assist you in managing these.

Take the online quiz

Disease Insight

Conditions & treatment options.

Female

Endometrial Hyperplasia

Endometrial hyperplasia is a condition of affecting the cells of the inner lining of the uterus (endometrium).

Also known as Uterine hyperplasia.

About the Condition

Endometrium is the lining of the womb (uterus), which is normally shed every month during the childbearing years, unless the woman conceives. Endometrial hyperplasia is overgrowth of the lining of the womb, beyond the normal 5 millimeters in thickness. It is also called endometrial hypertrophy. Hyperplasia can occur throughout the entire uterine lining, or may only affect an isolated area.

Endometrial hyperplasia is not cancer, but it can cause cellular changes that predispose an affected woman to developing cancer later. Most endometrial hyperplasia develops from a hormonal imbalance, where there is a dominance of estrogen and a deficiency of progesterone.

Next page: Symptoms of Endometrial Hyperplasia

ProFeme® 10

ProFeme 10 progesterone cream packaging

For women

ProFeme® 10% Progesterone Cream is specifically designed for use in women with declined or lowered progesterone levels.

Downloadable Resources

Symptoms of Endometrial Hyperplasia

Endometrial hyperplasia can begin as any of the following symptoms:

  • Vaginal discharge, especially if it has an odor
  • Dyspareunia, pain during sexual intercourse
  • Amenorrhea, lack of a menstrual period for more than 90 days, and you are not entering menopause
  • Menorrhagia, excessive bleeding greater than 80 milliliters (more than 16 soaked sanitary pads or 1/3 cup of blood) during the regularly expected menstrual period OR
  • Metrorrhagia, irregular uterine bleeding between expected menstrual periods OR
  • Menometrorrhagia, heavy and irregular uterine bleeding during the expected menstrual period and also at irregular, unexpected intervals
  • Polymenorrhea, bleeding too frequently, less than every 21 days OR
  • Post menopausal bleeding (PMB), when a woman over 40 who has not bled for at least 18 months resumes bleeding, AND her doctor has verified her menopause through blood tests for hormone levels
  • Difficult urination

Do not panic if you have any of these symptoms, however medical investigation is required. Well advanced uterine cancer causes pelvic pain, loss of appetite(anorexia), weight loss, and bowel and bladder changes.

Next page: Causes of Endometrial Hyperplasia

ProFeme® 10

ProFeme 10 progesterone cream packaging

For women

ProFeme® 10% Progesterone Cream is specifically designed for use in women with declined or lowered progesterone levels.

Downloadable Resources

Causes of Endometrial Hyperplasia

Common in women using high dose estrogens without adequate progesterone cover to protect against overgrowth of the uterine lining.

Occurs due to exposure to high dose estrogen (natural, HRT or OC) typical combined with low progesterone production. Often associated with other symptoms of estrogen dominance.

It can be caused as a result from the following conditions:

  • Using estrogen supplements alone, without progesterone, to suppress the effects of menopause
  • Progesterone deficiency
  • Polycystic ovary syndrome (PCOS)
  • Perimenopause
  • Inherited cancer of the bowel (hereditary non-polyposis colorectal carcinoma)
  • Using tamoxifen to suppress breast cancer
  • Obesity with diabetes
  • Ovarian tumor

Some cases can progress to cause Endometrial cancer.

Diagnosis

The condition is usually diagnosed through a Biopsy or ultrasound measuring endometrial thickness (> 5mm).

Abnormal uterine bleeding, or abnormal pap smear result.

Next page: Treatment for Endometrial Hyperplasia

ProFeme® 10

ProFeme 10 progesterone cream packaging

For women

ProFeme® 10% Progesterone Cream is specifically designed for use in women with declined or lowered progesterone levels.

Downloadable Resources

Treatment for Endometrial Hyperplasia

Endometrial hyperplasia is best managed by reducing the dose of estrogen being supplemented and adding the hormone progesterone or a progestagen (synthetic compounds with progesterone-like action on the uterus) to the treatment. Progesterone inhibits the overgrowth of the cells of the endometrium.

More severe cases may require a D & C - dilation and curettage - which is a surgical scraping of the lining of the uterus, or even a full hysterectomy if there is a chance of cancer.

Next page: Further information about Endometrial Hyperplasia

ProFeme® 10

ProFeme 10 progesterone cream packaging

For women

ProFeme® 10% Progesterone Cream is specifically designed for use in women with declined or lowered progesterone levels.

Downloadable Resources

Download our Booklet

Downloading our booklets is FREE.

Topics discussed in the Understanding Endometrial Hyperplasia booklet include:

  • What is endometrial hyperplasia?
  • Types of endometrial hyperplasia
  • What are my odds of developing cancer?
  • Why is hyperplasia dangerous?
  • What causes hyperplasia?
  • Who is at risk for hyperplasia?
  • What are the signs and symptoms of hyperplasia?
  • What is a normal cycle?
  • How can I decrease my symptoms?
  • How is hyperplasia treated?
  • What is the role of progesterone in humans?

Progesterone for Women FAQ's

ProFeme® 10

ProFeme 10 progesterone cream packaging

For women

ProFeme® 10% Progesterone Cream is specifically designed for use in women with declined or lowered progesterone levels.

Downloadable Resources

From our blog

View all posts

Newsletter sign up

Read previous newsletters